ADAPTIL Spray is the original dog pheromone spray, a clinically proven solution to help calm and comfort your dog on the go, especially during vet visits or other car travel. It works by mimicking calming "comforting messages" that mother dogs naturally release in the air called pheromones. Use when and where needed to provide targeted support for 4-5 hours at a time. Trusted by veterinarians and pet owners worldwide for over 15 years, more than 8 million dogs have benefitted from ADAPTIL dog calming products.