Dog urine odor is unmistakable, strong and extremely difficult to permanently remove. Now, with Urine Off Dog and Puppy Formula, you can permanently eliminate your dog's urine odor and stains from virtually any surface. Urine Off is a revolutionary biotechnology product that eliminates urine odor and stains at the source, permanently. Urine Off uses a combination of naturally occurring micro-organisms and their enzymes to digest the uric acid crystals (which produce urine's pungent aroma) as well as urea (the sticky substance in urine) and proteins (which promote pathogen growth).